Levodopa delivery systems: advancements in delivery of the gold standard. Expert Opin Drug Deliv. 2010 Feb;7(2):203-24. doi: 10.1517/ 17425240903483166.
Striatal levels of L-DOPA and dopamine demonstrated a 2.5-fold increase after i.p. administration of the liposomal formulation of the prodrug when compared ...
Discontinuous drug delivery resulting from the short half-life of l-dopa and erratic gastrointestinal absorption plays a major role in the ...
VANCOUVER—A liquid formulation of levodopa and carbidopa delivered continuously and subcutaneously is generally well tolerated and may reduce motor ...
L-DOPA-Coated Manganese Oxide Nanoparticles as Dual MRI Contrast Agents and Drug-Delivery Vehicles. Small. 2016 Jan 20;12(3):301-6. doi: ...
Preparation of Tween 80-Zn/Al-Levodopa-Layered Double Hydroxides Nanocomposite for Drug Delivery System. Aminu Umar Kura,1 Samer Hasan Hussein-Al- ...
A comprehensive study was conducted to investigate the effects of carrageenans, and hydroxypropylmethylcellulose (HPMC) on the properties ...
In the Earlier versus Late L-dopa (ELLDOPA) study, 200 mg of levodopa three times daily (t.i.d.) was more effective than 100 mg t.i.d., 50 mg t.i.d. ...
The US Food and Drug Administration approved the drug in 1970. Taming levodopa. Since then, L-DOPA has been the mainstay of Parkinson's ...
The current treatment is based on the replacement of dopamine, where precursor of DA Levodopa. (l-DOPA) is given orally. However, detrimental l-DOPA- has.