Introduction: Open fractures are plagued by high complication rates, among
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contaminated open fractures are frequently encountered in
Infectious complications of musculoskeletal trauma are an important factor
Objective: To determine if a dual-purpose bone graft can regenerate bone and reduce
attention to their patterns can help with avoiding wound-healing complications.
Dual-Purpose Bone Grafts Improve Healing and Reduce Infection
Cell metabolic activity, Live/Dead staining, double-stranded DNA (dsDNA) amounts, and alkaline phosphatase
Local antibiotic delivery into the wound at the time of surgical debridement
The treatment goals for open fractures are as follows:
In addition, with local delivery, the total drug amount may be reduced, yet the local