Abstract Hydrogels based on n‐alkyl methacrylate esters (n‐AMA), acrylic acid, and acrylamide crosslinked with 4 ...
colon, which is considered the optimum site for colon-targeted delivery of drugs.
Drug release kinetics revealed the controlled release pattern of
The drug- release profiles indicate that the amount of drug release depends on its degree of swelling and cross-linking. Keywords Colon, Cross-Linking, Hydrogel, ...
swelling behavior, permeability or mechanical strength and can control drug release
The goal was to obtain a colon-specific drug delivery system,
Keywords: pH sensitive hydrogels, swelling and drug release mechanism,
treatment of inflammatory bowel disease and ulcerative colitis.
Swelling behavior of hydrogels for colon-site drug delivery.
drugs targeted to colon based on pH control release along the pH change in the