To overcome the limitations of viral gene delivery systems, synthetic nonviral
In gene therapy, genetic materials, either RNA or DNA, are transferred into specific human tissues or cells to replace defective genes, substitute missing genes, ...
The simple mix of NLS-CTHD among these novel transfection enhancing peptides with DNA increased the gene transfer potency of cationic ...
We have developed polyelectrolyte gene delivery vectors that display
Evaluation of disulfide bond-conjugated LMWSC-g-bPEI as non-viral vector for low cytotoxicity and efficient gene delivery. Jeong GW(1), Nah ...
A drug delivery system (DDS) can overcome the above disadvantages of chemotherapy to a certain extent (8–12). Therefore, DDS research and ...
One of the most important requirements for non-viral gene delivery systems
KEYWORDS: gene delivery; nonviral; poly(amido amine); degree of branching; disulfide bond. Introduction. Gene therapy is a promising approach to treat ...
The present study constructed an effective disulfide bond-mediated cleavable RGD modified gene delivery system to overcome the ...
A frontier in the field of gene and protein therapy is RNA interference