Zinc-finger nucleases (ZFNs) are versatile reagents that have redefined genome engineering. Realizing the full potential of this technology ...
Due to an unexpected cell-penetrating property, zinc-finger nucleases (ZFNs) can be delivered to several mammalian cell types as proteins.
It has previously been shown that engineered zinc finger nucleases (ZFNs) can be packaged into adeno-associated viruses (AAVs) and ...
AAV-mediated delivery of zinc finger nucleases targeting hepatitis B virus inhibits active replication. PLoS One. 2014 May 14;9(5):e97579. doi: ...
We generated 3 zinc finger nucleases (ZFNs) that target sequences within the HBV polymerase, core and X genes. Upon the formation of ZFN- ...
We generated 3 zinc finger nucleases (ZFNs) that target sequences within the HBV polymerase, core and X genes. Upon the formation of ZFN- ...
AAV-Mediated Delivery of Zinc Finger Nucleases Targeting Hepatitis B Virus Inhibits Active Replication. Nicholas D. Weber,. Affiliations ...
With systemic viral delivery systems, this gene-editing approach corrected the mutant factor IX in models of mouse hemophilia.
Targeted egfp gene disruption by lentiviral delivery of ZFN proteins.
Will a ZFN insert a gene into my cell line? What is the best way to deliver the ...