Antibody-drug conjugates (ADC) are designed to be stable in circulation and to release potent cytotoxic drugs intracellularly following ...
Bispecifics are also applicable for payload delivery.
Currently, five bsAbs delivering payloads are in clinical trials, four of which target solid tumors. BsAb TF2, existing of three Fab fragments of which two target CEA ...
The binding specificities of the Fab arms are represented for each analysed molecule
Emerging delivery technologies for biotherapeutics have focused on
Rationale for delivery of cytotoxic drugs with monoclonal antibodies
... deliver for Ocean Infinity. By the end of this year, we expect to have completed delivery of more than 1,300 kWh of batteries to Ocean Infinity.
Nanocarriers for Doxorubicin Delivery: Self-Assembly,
... of applications, such as payload delivery, stabilization, guidance, navigation, etc. Compared with mono- and bi-propellant, ion, laser, plasma, Hall-effect and other thrusters, our solution ensures fabrication simplicity, affordability, robustness, ...
In this section, we introduce the microfluidic fabrication of these nanomaterials